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Cat. No. Product Name Target Signaling Pathways
T1583 Vorinostat

MK0683,伏立诺他,suberoylanilide hydroxamic acid,SAHA

Apoptosis; Mitophagy; Virus Protease; HDAC; Autophagy Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; Microbiology/Virology
Vorinostat (SAHA) 是一种泛的组蛋白脱乙酰酶 (HDAC) 抑制剂 (IC50=10 nM),对 HDAC1/2/3/6/7/11 均有抑制活性。 Vorinostat 具有抗肿瘤活性,可以诱导细胞分化,阻滞细胞周期,诱导细胞凋亡。
T36105 coumarin-SAHA

coumarin-Suberoylanilide Hydroxamic Acid,coumarin-SAHA

Suberoylanilide hydroxamic acid (SAHA) is a class I and class II histone deacetylase (HDAC) inhibitor that binds directly to the catalytic site of the enzyme thereby blocking substrate access. [1] coumarin-Suberoylanilide hydroxamic acid (c-SAHA) is a SAHA derivative where the anilino cap" group is replaced by 7-amino-4-methylcoumarin to produce a fluorescent probe that competitively binds HDAC. [2] The fluorescence excitation and emission maxima of free c-SAHA is 325 and 400 nm
T35765 SAHA-BPyne

Suberoylanilide hydroxamic acid (SAHA) is a class I and class II histone deacetylase (HDAC) inhibitor that binds directly to the catalytic site of the enzyme thereby blocking substrate access. SAHA-BPyne is a SAHA derivative with a benzophenone crosslinker and an alkyne tag intended to be used for profiling HDAC activities in proteomes and live cells. Such terminal alkyne groups can be used in linking reactions, known as click chemistry, characterized by high dependability and specificity of azi...

化合物

Vorinostat
Cat.No: T1583
Synonym: MK0683,伏立诺他,suberoylanilide hydroxamic acid,SAHA
Target: Apoptosis, Mitophagy, Virus Protease, HDAC, Autophagy
coumarin-SAHA
Cat.No: T36105
Synonym: coumarin-Suberoylanilide Hydroxamic Acid,coumarin-SAHA
Target:
SAHA-BPyne
Cat.No: T35765
Synonym:
Target:
TargetMol Loading
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